Abstract
Background There is a long-standing debate regarding the associations between area deprivation, urbanicity and elevated risk of severe mental illnesses (SMIs).
 Main Aim We investigated the associations between area deprivation, urbanicity and risk of SMIs in a population cohorts in Wales.
 Methods/Approach We extracted primary and secondary care electronic health records from 2004 to 2015 from Wales’s population. We identified prevalent and incident individuals with SMIs (schizophrenia related disorders and bipolar disorder) and their level of deprivation and urbanicity. We used the Welsh Index of Multiple Deprivation (WIMD) and urban/rural indicator to measure the level of area deprivation and urbanicity respectively for all lower layer super output areas, the geographic units used in the reporting of small area statistics comprised of approximately 1,500 individuals.
 Results Prevalence and incidence of SMIs is not evenly distributed in Wales. Increased prevalence and incidence of SMIs occur in more deprived and urban areas. Such associations occur for both schizophrenia related disorders and bipolar disorder and in both the primary and secondary care cohorts.
 Conclusion These findings have implications for resource allocation, service configuration and access to services in deprived communities, as well as, for broader public health interventions addressing poverty, and social and environmental contexts.
Highlights
Background with rationaleThere is a long-standing debate regarding the associations between area deprivation, urbanicity and elevated risk of severe mental illnesses (SMIs)
We investigated the associations between area deprivation, urbanicity and risk of SMIs in a population cohorts in Wales
We identified prevalent and incident individuals with SMIs and their level of deprivation and urbanicity
Summary
Background with rationaleThere is a long-standing debate regarding the associations between area deprivation, urbanicity and elevated risk of severe mental illnesses (SMIs). SC1*, Delpozo-Banos, M1, Lloyd, K1, Jones, I2, Walters, JTR2, Owen, MJ2, O‘donovan, M2, and John, A1
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