Abstract

Ovarian response indexes have been proposed in Assisted Reproductive Technology (ART) in order to optimize live birth rates (LBR), adjusting ovarian stimulation (OS) and minimizing risks. Gonadotropin doses are commonly adjusted according to ovarian reserve parameters, including antral follicle count (AFC), antimülerian hormone (AMH) and basal Follicle Stimulating Hormon (FSH) levels. The retrospective assessment of ovarian responses allows to identify three primary indexes: (i) Follicular output rate (FORT), the ratio of the number of pre-ovulatory follicles obtained at OS completion over AFC; (ii) Follicle oocyte index (FOI), the ratio of oocytes retrieved over AFC, and (iii) Ovarian sensitivity index (OSI), the ratio of oocytes retrieved over the total gonadotropin dose administered.

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