Are there effects of Extract Coffee Robust Lampung as Immunonutrition in Chicken against Salmonellosis?

Abstract

The poultry industry was an industry that supported the nutritional needs of all individuals and the world's food needs. Coffee was a natural ingredient consisting of antioxidant molecules such as Chlorogenic Acid (CGA). This research using ISA brown chicken layer, which divided into five groups such as healthy chicken (control group (C-)), chicken infected with Salmonella enteritidis 108 CFU/ml (control group (C+)), chicken infected with S. enteritidis 108CFU/ml and extract Coffee consecutive 500, 1000 and 1500 mg/kg body weight (BW) group (T1, T2, and T3). The relative level of TCD4, CD8, and CD45 cells was performed with One way ANOVA test. The research results showed that the relative level of TCD4+, TCD8+ and TCD45+ cells in T1 and T2 groups was not significant with the negative control group. The conclusion is that extracting Coffee in the T1 and T2 groups with a 500-1000mg/kg BW dose could regulate immune cell activation in chicken infected by S. enteritidis bacteria.