Abstract
The transformation of cortisol into prednisolone in cattle faeces was demonstrated and provided by literature, given the structural similarity of prednisolone with cortisol. In this study, we evaluated a possible neo-formation of prednisolone, as results of a faecal or environmental contamination. A saponine, α-solanine, and a sapogenin, diosgenin, were selected as possible precursors. A simple method without extraction was applied. The analyses were performed by HPLC–MS n to evaluate the possible transformations. The results showed that prednisolone was detected in the faecal suspension spiked with diosgenin at t= 8h, while cortisol was also detected at t = 24h in the sample of faeces spiked with α-solanine. In the feed and in the control samples, no transformations were observed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
