Abstract
Objective: The objective of present study was to find if antibiotics really benefit in preventing infection in lacerations anywhere in body, provided copious irrigation & meticulous surgical debridement is performed. Also, when wounds are contaminated. The study also took into consideration effect of length & depth of wound on wound infection. Methods: This longitudinal study was performed between November 2016 to June 2021 at Orthocare accident hospital & research center, India. Patients were allocated in two groups. Patients in Group A(n=221) were those who have received oral Amoxicillin & Clavulanic acid for 7 days as per standard protocol21and Group B (n = 189) patients did not receive antibiotics as per protocol in previous studies17. infection rate was measured in both group & measured outcome was analyzed with SPSS version 20, IBM. Categorical data was presented as percentages and analyzed with Chi square or Fisher Exact test.
Highlights
The objective of present study was to find if antibiotics really benefit in preventing infection in lacerations anywhere in body, provided copious irrigation & meticulous surgical debridement is performed
We found no significant difference in infection rate between Group A (2 out of 221) & group B (1 out of 189 patients), p < 0.05
Copious irrigation & meticulous debridement remain more crucial than antibiotics in preventing wound infection
Summary
Objective: The objective of present study was to find if antibiotics really benefit in preventing infection in lacerations anywhere in body, provided copious irrigation & meticulous surgical debridement is performed. The study took into consideration effect of length & depth of wound on wound infection. Infection rate was measured in both group & measured outcome was analyzed with SPSS version 20, IBM. Wound irrigation washes out debris & dilutes if antibiotics really benefit in preventing infection in lacerations bacterial load. Irrigation has no proven effect on wound anywhere in body, provided copious irrigation & meticulous healing & infection but most of the studies support it. The study took into consideration effect of saline for irrigation2'3’4’5’6. Wheeler et al recommended length & depth of wound on wound infection
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