Abstract

Background: Diagnosing with low-grade gliomas (LGGs) can be a very shocking and stressful experience, a traumatic event potentially leading to the development of posttraumatic stress symptoms (PTSS), and posttraumatic growth (PTG). Understanding how patients cognitively and behaviorally response to their diagnosing is also important to postoperative treatment. Thus, the current study explored the association between PTG and quality of life (QoL) of Chinese patients with LGGs. The moderation effects of coping strategies and PTSS on the relationship between PTG and QoL have been examined as well.Methods: Posttraumatic stress symptoms, Posttraumatic growth, coping strategies, and QoL were measured by using self-report surveys. Three hundred and thirty patients completed surveys approximately 1 month after surgery. We used three multiple regression models and added interaction terms in these models to test the moderation effects of PTSS and coping strategies on the relationship between PTG and QoL.Results: The results of hierarchical multiple regression suggested that PTG significantly predicted QoL, both PTSS and coping strategies moderated the association between PTG and QoL. Specifically, the association between PTG and QoL for patients who have non-significant PTSS is stronger than those who have significant PTSS. Furthermore, as the score of Avoidant Coping increases, the association between PTG and QoL becomes weaker.Conclusion: Posttraumatic growth may help to improve the QoL of LGGs patients, but PTSS and Avoidant Coping impeded the positive effect of PTG on QoL.

Highlights

  • Every year in China, approximately 15,000 individuals are diagnosed with low-grade gliomas (LGGs) (Chinese Glioma Collaboration Group and Chinese Glioma Genome Atlas, 2004; Lu et al, 2012)

  • The results of hierarchical multiple regression suggested that posttraumatic growth (PTG) significantly predicted quality of life (QoL), both posttraumatic stress symptoms (PTSS) and coping strategies moderated the association between PTG and QoL

  • Posttraumatic growth may help to improve the QoL of LGGs patients, but PTSS and Avoidant Coping impeded the positive effect of PTG on QoL

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Summary

Introduction

Every year in China, approximately 15,000 individuals are diagnosed with low-grade gliomas (LGGs) (Chinese Glioma Collaboration Group and Chinese Glioma Genome Atlas, 2004; Lu et al, 2012). Knowledge of psychological effect on QoL may be helpful for evaluating the prognosis of LGGs patients. Psychological factors (e.g., depression and posttraumatic stress symptoms) can have causal relationships with these variables at every level of the model (Wilson and Cleary, 1995). Based on this theoretical framework, this study emphasizes the influence of psychological factors on patients’ QoL, especially the influence of PTSS, PTG, and coping strategies. The current study explored the association between PTG and quality of life (QoL) of Chinese patients with LGGs. The moderation effects of coping strategies and PTSS on the relationship between PTG and QoL have been examined as well

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