Abstract
Background: Mucinous cystic neoplasms (MCN) of the pancreas are characterized by an inner layer of mucin-secreting cells and an ovarian-like stroma expressing estrogen and progesterone receptors. MCN have a potential for invasive degeneration and surgical resection is recommended by the international guidelines. Several case reports available in literature describe MCN undergoing a rapid increase in size during gestation. These case reports together with their histological characteristics created speculation about the possible interaction of MCN with hormones of gestation and systemic contraceptives. The aim of this study is to assess if pregnancy is a risk factor for malignant degeneration pancreatic MCN.
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