Abstract

Although a quarter of cervical cancers occur after the age of 65 years, there is no treatment consensus for these patients. The aim of this work was to survey how physicians treat patients with advanced cervical cancer, focusing on treatment adjustments according to age and frailty status. Specialists were invited to an online survey. Data collected included information on respondent and treatment strategy in four cases (FIGO IIb, FIGO IVa, FIGO IVb, metastatic recurrence) with three age scenarios (45-year-old, 75-year-old and fit, 75-year-old and unfit). We received 237 responses of which 117 were fully completed. Thirty-four percent of respondents reported they had available access to a geriatric team and 25% used a frailty screening tool in routine. Therapeutic strategies did not differ between young and old fit patients. However, treatment modalities and intensity were different for old and unfit patients. Physicians answered that they would treat old fit patients as their younger counterparts but would reduce treatment intensity for old unfit patients. However, even if they were willing to adapt their treatment strategy based on frailty status, most of them do not use the tools that would allow distinguishing “fit” and “unfit” older patients, leaving room for improving accurate geriatric evaluation.

Highlights

  • Cervical cancer is the second most common cancer in women with 500.000 new cases every year

  • The questionnaire was anonymously sent by email to gynecological surgeons, radiotherapists, medical oncologists, and geriatricians through networks from the young committee of the Société Internationale d’Oncologie Gériatrique (Young SIOG), the young network of the European Society of Gynaecological Oncology (ENYGO), the European Organization for Research, and Treatment of Cancer (EORTC; gynaecological cancer group, radiation oncology group, and cancer in elderly task force), and the Association d’Enseignement et de Recherche des Internes en Oncologie (AERIO, French national association of residents in oncology)

  • Fifty-five were surgeons (47%), 33 (28%) were radiation oncologists, 52 (44%) were chemotherapy prescribers, and 16 (14%) were geriatricians or physicians trained in geriatric oncology

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Summary

Introduction

Cervical cancer is the second most common cancer in women with 500.000 new cases every year. Older patients often present with later stages of cervical cancers [3]. The benefit-risk balance for these treatments among older patients has been poorly studied. Older patients are at increased risk of treatment toxicity [6]. For all these reasons, treatment of cervical carcinoma is not consistent in the geriatric population. The aim of this study was to survey the treatment attitudes of gynecological cancer specialists for cervical cancer according to age and health status

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