Are hepatocyte growth factor‐like protein and macrophage stimulating protein the same protein?

Abstract

Protein ScienceVolume 2, Issue 4 p. 666-668 For the RecordFree Access Are hepatocyte growth factor-like protein and macrophage stimulating protein the same protein? Jorge A. Bezerra, Jorge A. Bezerra Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorSu Han, Su Han Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorMary Jo S. Danton, Mary Jo S. Danton Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorSandra J. Friezner Degen, Corresponding Author Sandra J. Friezner Degen Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Division of Basic Science Research, Children's Hospital Research Foundation, Elland and Bethesda Avenues, Cincinnati, Ohio 45229–2899Search for more papers by this author Jorge A. Bezerra, Jorge A. Bezerra Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorSu Han, Su Han Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorMary Jo S. Danton, Mary Jo S. Danton Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Search for more papers by this authorSandra J. Friezner Degen, Corresponding Author Sandra J. Friezner Degen Division of Basic Science Research, Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229Division of Basic Science Research, Children's Hospital Research Foundation, Elland and Bethesda Avenues, Cincinnati, Ohio 45229–2899Search for more papers by this author First published: April 1993 https://doi.org/10.1002/pro.5560020416Citations: 20AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Bhargava, M., Joseph, A., Knesel, J., Halaban, R., Li, Y., Pang, S., Goldberg, I., Setter, E., Donovan, M.A., Zarnegar, R., Michalopoulos, G.A., Nakamura, T., Faletto, D., & Rosen, E.M. (1992). Scatter factor and hepatocyte growth factor: Activities, properties and mechanism. Cell Growth Differ. 3, 11– 20. 2 Bottaro, D.P., Rubin, J.S., Faletto, D.L., Chan, A.M.-L., Kmiecik, T.E., Vande Woude, G.F., & Aaronson, S.A. (1991). Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251, 802– 804. 3 Han, S., Stuart, L.A., & Degen, S.J.F. (1991). Characterization of the DNF15S2 locus on human chromosome 3: Identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. Biochemistry 30, 9768– 9780. 4 Leonard, E.J. & Skeel, A. (1976). A serum protein that stimulates macrophage movement, chemotaxis and spreading. Exp. Cell Res. 102, 434– 438. 5 Michalopoulos, G.K. & Zarnegar, R. (1992). Hepatocyte growth factor [editorial]. Hepatology 15, 149– 155. 6 Nakamura, T., Nishizawa, T., Hagiya, M., Seki, T., Shimonishi, M., Sugimura, A., Tashiro, K., & Shimizu, S. (1989). Molecular cloning and expression of human hepatocyte growth factor. Nature 342, 440– 443. 7 Naldini, L., Vigna, E., Narsimhan, R.P., Gaudino, G., Zarnegar, R., Michalopoulos, G.K., & Comoglio, P.M. (1991). Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene 6, 501– 504. 8 Skeel, A., Yoshimura, T., Showalter, S.D., Tanaka, S., Appella, E., & Leonard, E.J. (1991). Macrophage stimulating protein: Purification, partial amino acid sequence, and cellular activity. J. Exp. Med. 173, 1227– 1234. Citing Literature Volume2, Issue4April 1993Pages 666-668 ReferencesRelatedInformation