Are Corticosteroids Beneficial in ARDS

Abstract

In 1998, a very small randomized trial suggested that a prolonged course of moderate-dose corticosteroid therapy, starting after at least 1 week of mechanical ventilation, was beneficial for patients with acute respiratory distress syndrome (ARDS; Journal Watch Jul 21 1998). Finally, a larger randomized multicenter U.S. trial has been completed. The investigators enrolled 180 mechanically ventilated patients with ARDS of least …