Abstract

SummaryIntra‐articular corticosteroids are an effective treatment for equine osteoarthritis, however, there is increasing evidence for the effectiveness of other treatments such as biologics. Whilst current evidence does support biologics and their use in patients diagnosed with osteoarthritis, there remains to be a lack of evidence regarding their long‐term outcomes and the efficacy of their use as a treatment, especially when compared to corticosteroids. This paper reviewed the evidence comparing intra‐articular corticosteroids and biologics in the treatment of equine osteoarthritis and found that whilst they are both effective treatments, more evidence directly comparing them is required.

Highlights

  • Do biologics, such as autologous conditioned serum and autologous processed plasma, show an improved clinical outcome and prognosis compared to corticosteroids when treating osteoarthritis in equids?

  • Investigated the treatment of experimentally induced osteoarthritis (OA) in horses with either autologous conditioned serum (ACS) or placebo (Phosphate Buffered Saline; PBS) as control. 16 horses were split into two groups of 8; placebo (PBS) or treatment (ACS)

  • Without further studies implicating the use of biologics as a treatment when clinical signs first present, it is difficult to ascertain their effectiveness as a firstline treatment, and so further studies relating to the stage of OA that biologics are used for treatment are required

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Summary

Summary

Intra-articular corticosteroids are an effective treatment for equine osteoarthritis, there is increasing evidence for the effectiveness of other treatments such as biologics. Whilst current evidence does support biologics and their use in patients diagnosed with osteoarthritis, there remains to be a lack of evidence regarding their long-term outcomes and the efficacy of their use as a treatment, especially when compared to corticosteroids. This paper reviewed the evidence comparing intra-articular corticosteroids and biologics in the treatment of equine osteoarthritis and found

CAB Direct
Refining the question
Quality and quantity of evidence found
Prospective randomised controlled trial
Can this evidence be applied to my case population and conclusions?
Prospective randomised blinded controlled clinical trial
Source of funding
Full Text
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