Arctium lappa and Arctium tomentosum, Sources of Arctii radix: Comparison of Anti-Lipoxygenase and Antioxidant Activity as well as the Chemical Composition of Extracts from Aerial Parts and from Roots.

Weronika Skowrońska,Sebastian Granica,Magdalena Dziedzic,Agnieszka Bazylko,Maria Ziaja,Justyna Kurkowiak

doi:10.3390/plants10010078

Weronika Skowrońska, Sebastian Granica + Show 4 more

Open Access

https://doi.org/10.3390/plants10010078

Copy DOI

Abstract

Arctium lappa is a weed used in traditional medicine in the treatment of skin inflammation and digestive tract diseases. Arctium tomentosum is used in folk medicine interchangeably with Arctium lappa and, according to European Medicines Agency (EMA) monography, provides an equal source of Arctii radix (Bardanae radix), despite the small amount of research confirming its activity and chemical composition. The aim of the study was the comparison of the anti-lipoxygenase and the antioxidant activity, scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH), superoxide anion (O2•−), and hydrogen peroxide (H2O2), of 70 % (v/v) ethanolic extracts from the aerial parts and the roots of Arctium lappa and Arctium tomentosum. In the tested extracts, the total polyphenols content and the chemical composition, analyzed with the HPLC–DAD–MSn method, were also compared. The extracts were characterized by strong antioxidant properties, but their ability to inhibit lipoxygenase activity was rather weak. A correlation between the content of polyphenolic compounds and antioxidant activity was observed. The extracts from A. lappa plant materials scavenged reactive oxygen species more strongly than the extracts from A. tomentosum plant materials. Moreover, the extracts from A. lappa plant materials were characterized by the statistically significantly higher content of polyphenolic compounds.

Highlights

No statistically significant differences were found in the activity between Arctium lappa and Arctium tomentosum plant materials’
The conducted research shows too many significant differences between the extracts of Arctium lappa and Arctium tomentosum for these two species to be considered as providing equivalent plant material
To the best of our knowledge, there is no available texts in the literature that provide data on the comparison of the antilipoxygenase and the antioxidant activity, as well as the chemical composition between raw materials obtained from the two tested species

Summary

Introduction

Arctium lappa L., commonly known as the greater burdock, is a species from the Asteraceae family that grows in Europe, Asia, and North America [1]. It is a biennial plant, flowering from July to October. It grows commonly in Poland, especially in the ruderal places, near the water reservoirs, roadsides, and outbuildings [2]. Burdock plant is very popular in East Asian cuisine. It is harvested and eaten as a root vegetable, but its immature flowers, stalks, and young leaves are used as food

Objectives

Methods

Results

Conclusion