Abstract
Arctigenin isolated from the medicinal herb Arctium lappa used for treatment of inflammation has been shown to decrease IgE in human B cells. Both naïve and memory B cells are capable of telomere lengthening and upregulating Telomerase activity in response to activation signals maintaining the replicative potential of GC and descendant memory B cells. In this study we investigated whether Arctigenin inhibits the gene expression of telomere and hTERT – human telomerase reverse transcriptase in human B cell line.
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