Arctigenin: A Potential Component with Multifaceted Therapeutic Properties

Abstract

Medicinal plants are an excellent source of new therapeutic drugs because of their phytochemical constituents. Arctium lappa L. (common name-burdock) is a perennial medicinal herb commonly found in China, Japan, Korea traditionally used as promising health supplement. promising health supplement. Major active constituent of A. lappa L. seeds are arctigenin which exhibits pharmacological potential such as anti-inflammatory, anticancer, antimicrobial and hepatoprotective properties. The purpose of this study is to provide an up-to-date evaluation of the literature on the pharmacological activities of Arctigenin from Articum lappa L. Literature is collected from Google scholar, Science Direct, Research Gate, PubMed, Google, and SciFinder databases published between 2012 and 2021 (Jan). Keywords used to retrieve the data are pharmacological profile, arctigenin, and Arctium lappa L. The antioxidant, anti-inflammatory, anti-tumor, hepatoprotective, renoprotective, neuroprotective, and CNS depressant properties of arctigenin demonstrated its pharmacological significance among traditional science According to different research, arctigenin is effective in the treatment of a variety of chronic disorders, including cancer (stomach, lungs, liver, and colon) and inflammatory diseases (rashes, and other skin conditions.). Future experiments based on the mechanism pathway responsible for the protective role of arctigenin's will help the scientist to uncover its health benefits.