Abstract

Simple SummaryBreast cancer is leading cancer increases the death rate in women. Early diagnosis of breast cancer in women can save their lives. The current study proposed a novel scheme to detect architectural distortion from mammogram images to predict breast cancer using a deep learning approach. Results are evaluated on a public and a private dataset which may help to improve the diagnostic ability of breast cancer of radiologists and doctors in daily clinical routines. Furthermore, the proposed method achieved maximum accuracy as compared with previous approaches. This study can be interesting and valuable in the healthcare predictive modeling domain and will add a real contribution to society.Architectural distortion is the third most suspicious appearance on a mammogram representing abnormal regions. Architectural distortion (AD) detection from mammograms is challenging due to its subtle and varying asymmetry on breast mass and small size. Automatic detection of abnormal ADs regions in mammograms using computer algorithms at initial stages could help radiologists and doctors. The architectural distortion star shapes ROIs detection, noise removal, and object location, affecting the classification performance, reducing accuracy. The computer vision-based technique automatically removes the noise and detects the location of objects from varying patterns. The current study investigated the gap to detect architectural distortion ROIs (region of interest) from mammograms using computer vision techniques. Proposed an automated computer-aided diagnostic system based on architectural distortion using computer vision and deep learning to predict breast cancer from digital mammograms. The proposed mammogram classification framework pertains to four steps such as image preprocessing, augmentation and image pixel-wise segmentation. Architectural distortion ROI’s detection, training deep learning, and machine learning networks to classify AD’s ROIs into malignant and benign classes. The proposed method has been evaluated on three databases, the PINUM, the CBIS-DDSM, and the DDSM mammogram images, using computer vision and depth-wise 2D V-net 64 convolutional neural networks and achieved 0.95, 0.97, and 0.98 accuracies, respectively. Experimental results reveal that our proposed method outperforms as compared with the ShuffelNet, MobileNet, SVM, K-NN, RF, and previous studies.

Highlights

  • Breast cancer is leading cancer worldwide in 2020, with 11.7% overall reported cases per world health organization [1] and one of the major causes of death in women

  • The computer vision-based image preprocessing method has pertained to detecting the architectural distortion ROIs from digital mammograms for all models

  • The manual interpretation of Architectural Distortion is a challenging task for radiologists to figure out abnormalities during the examination of mammograms due to its subtle appearance on fatty denser mass

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Summary

Introduction

Breast cancer is leading cancer worldwide in 2020, with 11.7% overall reported cases per world health organization [1] and one of the major causes of death in women. The mortality rate was increased from 6.6% to 6.9% this year due to breast cancer These breast cancer tumors are screened on an X-ray machine for breast cancer diagnosis and manually interpreted by the radiologist to predict benign and malignant tumors. Screening methods such as ultrasound, and mammography are used to diagnose breast cancer, while the standard screening method is mammography at the early stage. Architectural distortion (AD) is the third most suspicious appearance on a mammogram representing abnormal regions that can be found visible on mammography projection [3] The main parameters such as global asymmetry, focal asymmetry, and developing asymmetry of tissue can be calculated using machine and deep learning algorithms to track AD in mammograms. The ILC and IDC on mammography having a star-shaped pattern are likely to be malignant, while the complex and radial sclerosing lesions architectural distortion having larger than 1 cm is probably benign [4]

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