Abstract
Human exposure to chemicals may occur via different human contact sites and target organs (such as discussed in Chap. 2), and also under a variety of exposure scenarios; broadly speaking, an exposure scenario is a description of the activity that brings a human receptor into contact with a chemical material, product, or medium. Chemical exposure investigations (typically consisting of the planned and managed sequence of activities carried out to determine the nature and distribution of hazards associated with potential chemical exposure problems) can be properly designed to help define realistic exposure scenarios—and then subsequently used to address human exposure and likely response to chemical toxicants.
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