Abstract

e4 www.thelancet.com Vol 378 November 5, 2011 3 Flora SJ, Pachauri V. Chelation in metal intoxication. Int J Environ Res Public Health 2010; 7: 2745–88. 4 Bradberry S, Vale A. Dimercaptosuccinic acid (succimer; DMSA) in inorganic lead poisoning. Clin Toxicol 2009; 47: 617–31. 5 Anon. Investigation into blood lead poisoning case in Jiahe, Hunan. Xinhua News March 16, 2010. http://news.xinhuanet.com/ politics/2010-03/16/content_13178998_6. htm (accessed June 14, 2011). can be exposed to toxic plasticisers through ingestion, inhalation, and dermal exposure. DEHP, the most commonly used and produced phthalate, has been widely detected in the environment including water, air, soil, and food products in China (table). The latest (unpublished) data from our laboratory show an average concentration of DEHP of 0·472 μg/L and a concentration of dibutyl phthalate (DBP) of 0·563 μg/L in drinking water in Shanghai. Other studies indicate that the estimated daily intakes of DEHP and DBP for Chinese people exceeded the reference dose of the US Environmental Protection Agency and the tolerable daily intake of the European Food Safety Authority. In view of the environmental ubiquity of plasticisers in China, short-term and long-term eff ects of environmental exposure to toxic plasticisers on population health should be regarded as a research priority to provide urgently needed information for proper interventions.

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