AR Gene

Abstract

The purpose of this study is to identify the effects of aerobic exercise as the polymorphism in the β3-AR gene of obese children. For this study, 30 children, who is over 25% BMI and do not regularly exercise, were randomly assigned to 2groups. One group is normal group(Trp64Trp, 23children) and the other one is mutation group(Trp64Arg, 7children). Body composition factors and physical abilities were measured before and after exercise program. Blood was collected from vein about 10㎖ and blood analyses were requested. Paired t-test and one-way repeated measured ANOVA were used as the statistical analysis, and significance was accepted at p＜.05. From the statistical analysis results for the body composition, and physical fitness, the following conclusions could be obtained. After aerobic exercise, body compositions of obese children are significantly changed in height (+0.4%), BMI (-1.3%), body fat mass (-2.3%), percent body fat(-2.0%)(p＜.05). Physical fitness of obese children are significantly changed in muscular strength (+12.9%), muscular endurance (+23.3%), flexibility(+11.8%)(p＜.05). After aerobic exercise, there was significantly changed in hight(+0.4%), BMI (-1.2%), body fat mass (-2.4%), percent body fat(-2.0%), muscular strength (+16.2%), muscular endurance (+16.0%), flexibility (+14.0%), cardiovascular endurance (-3.7%), The difference within groups was only muscular strength. In this study, aerobic exercise was found more effective for the enhancement of body composition, blood lipid, physical fitness The β3-AR in normal group was more different after exercise to compare with gene alteration group so that obese is more influence for gene.