Abstract
An aqueous-venus shunt in normal and buphthalmic rabbit eyes had remarkable effects on aqueous humor dynamics 12 months after operation or as long as the shunt Was patent. Improvement in outflow facility did not seem to be associated with an appreciable change in the rate of aqueous formation. The implanted tube was well tolerated. The abnormalities found in angle structures of rabbits with hereditary buphthalmia may be responsible for decreased outflow facility. They were somewhat similar to abnormalities occasionally seen in congenital glaucoma in humans. The method of establishing an aqueous-venous shunt and its early effects on intraocular fluid dynamics in normal and hereditarily buphthalmic rabbits(superscript 1, 2) and in normal monkey eyes(superscript 3) have been described. A decrease in intraocular pressure and increase in outflow facility were observed in eyes with a patent shunt. This report presents later observations of changes in aqueous dynamics and also histological studies of the original eyes one year after operation.
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