Approximation of electron capture response factors for highly electrophilic compounds

Abstract

A theoretical upper limit of electron attachment rate constants is derived, based on collision-limited electron interaction with polarizable molecules. This limit is shown to give upper limits for electron capture response factors. Evidence is presented showing that this limit is approached to within a factor of two for a wide variety of highly electrophilic compounds. It is suggested that this limit can be used as an approximation for electron capture response factors for suitable compounds, and that properly chosen derivatizing reagents may allow detection of derivatives with fairly accurate prediction of response factors.