Abstract

The proportion of people aged >65 years in the European Union is expected to rise from 84 million in 2008 to 141 million by 2050.1 Older people are the main consumers of medicines.2 The use of medicines in advanced age is associated with increased risks from age-related changes in pharmacokinetics, pharmacodynamics, multimorbidity and polypharmacy. Polypharmacy is the most consistent predictor of drug-related problems (DRPs) such as drug use without an indication, adverse drug interactions, subtherapeutic dosage, overdosage, non-compliance …

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