Approaches towards Influenza Vaccine

Abstract

Influenza viruses still constitute a true public ill health today. The influenza an epidemic was isolated for the primary time in 1931, and therefore the first attempts to develop a vaccine against the virus began soon afterwards. Additionally to causing seasonal epidemics, influenza viruses can cause pandemics randomly intervals, which are very hard to predict. Vaccination is that the best way of preventing the spread of influenza infection. However, seasonal vaccination is ineffective against pandemic influenza viruses due to antigenic differences, and it takes approximately six months from isolation of a replacement virus to develop an efficient vaccine. To deal with the emergence of latest circulating strains, but also the emergence of resistant strains to classic antivirals, it's necessary to develop new antiviral approaches. One among the possible ways to fight the emergence of pandemics could also be by employing a new sort of vaccine, with an extended and broad spectrum of action. The extracellular domain of the matrix protein 2 (M2e) of Influenza an epidemic may be a conservative region, and a beautiful target for a universal influenza vaccine.