Abstract
The approach to fever in the neutropenic host in large part depends on an understanding of the basic immune defect. White blood cells are critically important in maintaining an infection-free state. Nearly 30 years ago, the risk of serious bacterial infections in patients with a low number of circulating leukocytes was first recognized by Bodey and coworkers [1]. Diminished polymorphonuclear leukocyte numbers or function and impaired humoral immunity result in the development of serious infections, with the attendant risk of morbidity and mortality.
Published Version
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