Abstract
BackgroundCommunity-acquired pneumonia (CAP) remains a major cause of morbidity and mortality worldwide among children. The growing number of guidelines have been accompanied with a growing concern about variance and conflicts among guideline recommendations. There is a need to critically appraise clinical practice guidelines (CPGs) in order to ensure safe and effective practices.MethodsA literature search was systematically conducted in English and Chinese major academic databases (from January 2000 to March 2015). CPGs related to CAP in children were evaluated by four independent assessors, according to AGREE II instruments. Standardized domain scores were calculated for each guideline. Inter-rater reliability was assessed by intraclass correlation coefficient. The software used for analysis was SPSS 17.0.ResultsA total of 10 guidelines met the inclusion criteria and were appraised. Scope and purpose (69.03 %) and clarity of presentation (83.33 %) achieved relative high scores, while the scores of the other four domains were low: stakeholder involvement (42.78 %), rigour of development (44.95 %), applicability (37.60 %), and editorial independence (23.74 %). 3 guidelines were strongly recommended as a result of the overall scores were greater than 60 %.ConclusionThe qualities of CPGs for CAP in children were generally acceptable with several flaws. Stakeholder involvement, rigour of development, applicability and editorial independence should be considered and well described in the future development of CPGs.
Highlights
Community-acquired pneumonia (CAP) remains a major cause of morbidity and mortality worldwide among children
Community-acquired pneumonia (CAP) is defined as an acute infection of lower respiratory tract occurring outside hospital
It remains a major cause of morbidity and mortality among children in developing and developed countries
Summary
Community-acquired pneumonia (CAP) remains a major cause of morbidity and mortality worldwide among children. Community-acquired pneumonia (CAP) is defined as an acute infection of lower respiratory tract occurring outside hospital. It remains a major cause of morbidity and mortality among children in developing and developed countries. CAP has an incidence of 0.29 episodes per child-year and a mortality rate of 1.3–2.6 % [1, 2]. The incidence of CAP is lower in developed countries, with an incidence of about 0.05. Guidelines for the management of CAP in children have been increasingly produced and disseminated in recent years. Globalization and uniformity between centers worldwide in patient management has become a trend. There can be huge differences between countries or regions in respect
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