Abstract
The present paper describes the course of disease in the severely affected left eye of a 14-year-old girl from a family in which mesodermal developmental anomalies of the anterior segment occurred frequently. In the course of 18 years there was slight progression of the existing corneal opacity. During the last 2 years a decompensation of the endothelium occurred, with cornea guttata. After conservative treatment had failed a therapeutic extended-wear lens was fitted as an epithelial bandage, with successful results. The cosmetic defect was finally eliminated with an iris lens.
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