Abstract

Optical cochlear implant is an emerging applied technology of stimulating auditory neurons by using pulsed laser light as a stimulus to evoke neural activity instead of electrical currents. Laser stimulation has more potential in accuracy and high frequency resolution than electrical stimulation. In this paper we demonstrated a fiber laser system (980nm) to irradiate on guinea pig cochlear in vivo for the first time. The pulsed laser stimulation successfully evoked auditory nervous impulse, similar to acoustic stimulation. And the performance under different laser pulse intensity and pulse width is further tested and discussed. The results show that the 980nm pulsed laser stimulation with microsecond level width is effective and safe to evoke auditory response. Photoacoustic or photothermal effects maybe the main mechanism. In the end, we put forward some prospects of the applied technology in cochlear implant.

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