Abstract
Applied RNAi: from fundamental research to therapeutic applications
Highlights
Edited by: Subbaya Subramanian, University of Minnesota, USA Reviewed by: Reena V
One of the most exciting aspects of the genomic era during the last fifteen years has been the discovery of RNA interference pathways and their key function in gene regulation in eucaryotes
The road toward the therapeutic use of RNAi in human has proven to be more tortuous than anticipated with difficulties in minimizing several off-target effects, and it is becoming clear that this strategy can only succeed in a limited number of diseases at present
Summary
Edited by: Subbaya Subramanian, University of Minnesota, USA Reviewed by: Reena V. Applied RNAi: from fundamental research to therapeutic applications
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