Abstract
The BEVALAC is a compound accelerator capable of producing energetic charged particle beams. These high-energy ion beams have been used in multidisciplinary research related to fundamental radiobiology and cancer therapy. Selected examples of research areas under investigation are presented. Available data on the phenomena of nuclear fragmentation and microscopic distribution of energy deposition are given as examples of research in physics with high-LET charged particles. Dose-response data are provided for cell survival and cell mutation end points which demonstrate the greater efficiency of BEVALAC ions compared to X-rays. The usefulness of nuclear secondaries (radioactive beams) in diagnostic studies is described from the point of view of Bragg peak therapy. The results of the last fourteen years of high-LET research have generated interest in the construction of hospital-based medical accelerators.
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