Abstract
As one of optical technique, surface plasmon resonance (SPR) shows a superb interdisciplinary usage for detection. A diverse of different SPR-based biosensors have been constructed and been used for various fields, such as biomedicine, environmental monitoring and food safety. This research outlines the basic concepts, the working principle of SPR and the applications of SPR in biomedicine. In addition, the discovery and development of SPR will be present, as well as the mechanism behind SPR instruments. It will also be examined in detail the application of SPR in drug analysis and early diagnosis of cancer. Some perspectives about the latest research advances and future development areas will also be discussed respectively. The advantages and disadvantages of SPR will be illustrated throughout this work.
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