Abstract

The use of recombinant DNA as a routine diagnostic tool is now a reality. Although gene probes have been available to academic researchers for a number of years, only recently has progress in recombinant DNA technology made it possible to extend their use to the screening of large numbers of samples, and make such analytical procedures part of the normal workload of hospital, analytical and commercial laboratories. It is now possible to detect genetic diseases in patients or at risk populations, and to diagnose infectious disease or identify infectious agents present as environmental contaminants. The technology can also be extended to the unambiguous identification of individuals for forensic, paternity or immigration purposes. The application of recombinant DNA technology is therefore of interest to scientists from a wide variety of disciplines.

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