Abstract

The increasing frequency of renal transplantation has stimulated the development of diagnostic methods of evaluating the functional integrity of the graft. Radionuclide techniques have achieved great popularity in this regard. Although clearance studies, fibrinogen uptake, and conventional probe renography have been used with success, the imaging studies of the kidney recently have been of particular interest. Sequential scintiphotography with 131I Hippuran has been shown to facilitate the diagnosis of problems such as vascular thrombosis, acute tubular necrosis, acute and chronic rejection, urinary extravasation, and ureteral obstruction. Although the appearance of the kidney in any one study may be diagnostic, it is of much greater value to observe improvement or deterioration of function studies with bolus injections of 99mTc pertechnetate to establish the patency of the newly anastomosed vascular pathways.

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