Applications of microarray technology to pancreatic cancer research and drug development

Abstract

As one of the deadliest forms of malignancy in the US and worldwide, pancreatic cancer is becoming a top research priority as therapies at present have had markedly limited or no success in controlling this disease. The arrival and advancement of microarray technology in the last decade offers the hope of new diagnostic, prognostic and therapeutic applications. The purpose of this review is to describe the basic principles of microarray technology and techniques and its use in pancreatic cancer research for drug discovery and development, with a focus on the relevant published data obtained from the literature.