Abstract
This paper describes the advantages and disadvantages of drug discrimination (DD) procedures as methods for obtaining information about the properties of drugs that underlie drug abuse. The paper (1) describes the DD behavioral procedures that are available, (2) enumerates the properties of these procedures that are advantageous for the study of drug effects that cause drug abuse, (3) summarizes properties of DD procedures that are disadvantageous for the study of preclinical psychopharmacology in general and of drug abuse in particular, (4) discusses the face validity of DD procedures, (5) reviews evidence supporting the idea that “sensory” or subjective effects of drugs mediate the formation of DDs, (6) reviews evidence that is not supportive of this explanation for DDs, and (7) describes the types of studies relevant to drug abuse that can be conducted with DD procedures.
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