Application value of vascular embolization combined with body surface injection of sclerosing agent in treatment of hemangioma in children with rich blood supply

Abstract

Objective: To evaluate the clinical efficacy of vascular embolization combined with body surface injection of sclerosing agent for the treatment of high-flow hemangiomas in children. Methods: A total of 38 cases were enrolled in the study, including 28 cases with maxillofacial hemangiomas, 10 cases with limbs hemangiomas, and 6 cases with upper limb hemangiomas. The treatment plans were as follows: PVA with iodinated oil in 11 cases, PVA with bleomycin in 5 cases, and PVA with iodinated oil and bleomycin in 22 cases. A foam sclerosing agent mixture (bleomycin+1 ml add polyol+4 ml add air+1 ml dexamethasone+1 ml contrast medium) was injected into the angioma through the surface, and the involuting condition and related complication were recorded. Results: There was no complication in all patients, among which 18 children’s hemangiomas faded away in regular follow-up after one treatment, 13 children’s hemangiomas partly faded away and local symptom disappeared in regular follow-up after transcatheter arterial embolization combined with body surface injection sclerotherapy, 4 children's hemangiomas faded away after body surface injection sclerotherapy for two or three times, 3 children's hemangiomas size decreased after transcatheter arterial embolization, 1 child loss to follow-up, 1 child went to sugery therapy, and 1 child was with drug therapy. Conclusion: Transcatheter arterial embolization combined with body surface injection sclerotherapy is an important method which could be the preferred treatment in high-flow hemangiomas in children. Key words: Hemangiomas in children; Transcatheter arterial embolization; Sclerosing agent