Application value of two-dimensional combined four-dimensional ultrasound in the diagnosis of prenatal fetal malformation

Abstract

Objective To investigate the application value of two-dimensional combined four-dimensional ultrasound in the diagnosis of prenatal fetal malformation. Methods A total of 1 532 pregnant women from January 2013 to February 2018 in Huozhou People’s Hospital were selected for retrospective analysis on prenatal ultrasound examination data. A total of 1 532 pregnant women were screened by two-dimensional ultrasound for prenatal screening, two-dimensional ultrasound and four-dimensional ultrasound examination were performed on those suspected fetal malformation, and the examination results were compared with the results of induction or delivery. The diagnostic effect of two-dimensional ultrasound and two-dimensional combined with four-dimensional ultrasound fetal malformation was companed. Results In 1 532 pregnant women, 40 cases of malformed fetuses were confirmed by childbirth or induction of labor. Two-dimensional combined with four-dimensional ultrasound checked out 39 cases of malformed fetus. The diagnostic sensitivity of two-dimensional combined with four-dimensional ultrasound (95.00%) was higher than that of two-dimensional ultrasound (75.00%), and the positive predictive value (97.44%) was higher than that of two-dimensional ultrasound (43.48%), The difference was significant (P<0.05). After delivery or induction of labor, the number of deformities was 52, two-dimensional combined with four-dimensional ultrasound diagnosis missed 4 cases of fetal malformation, and misdiagnosed 2 cases; two-dimensional ultrasound diagnosis missed 12 cases of fetal malformation, misdiagnosed 71 cases. Conclusions Two-dimensional combined with four-dimensional ultrasound has higher diagnostic sensitivity and positive predictive value for prenatal fetal malformation, which has less missed diagnosis and misdiagnosis, and can detect fetal malformation in time. So it is beneficial to the quality of birth population in China. Key words: Two-dimensional ultrasound; Four-dimensional ultrasound; Fetal malformation