Application value of red blood cell distribution width in the prognosis of chronic heart failure patients

Abstract

Objective To explore the influence of red blood cell distribution width(RDW) in the prognosis of chronic heart failure(CHF) inpatient. Methods A total of 120 chronic heart failure in-patients received in Yangchun Hospital of Traditional Chinese Medicine from August 2015 to April 2016 were selected as the research objects. According to the cardiac functional grading of NYHA, these in-patients were divided into mild failure group at 78 (mild group, cardiac functional grading I and II), severe failure group at 42 in-patients (severe group, cardiac functional grading III and IV). According to RDW, the inpatients were divided into abnormal group at 43(RDW>15.5) and normal group at 77(RDW<15.5). The indices such as hemoglobin (Hb) concentration, red blood cell count(RBC), haematocrit(Hct), RDW and LVEF of mild group were compared with it of severe group. In addition, during the hospital stay, the malignant arrhythmia, cardiac failure exacerbation (recurrent) and case fatality rate of red blood cell distribution width abnormal group were compared with normal group. Results The Hb, RBC, Hct, LVEF and RDW of mild group were respectively(137.35±18.23)g/L, (4.40±0.38)×1012/L, (40.64±6.45)%, (58.17±5.82)% and (13.06±1.12). The difference from severe group had statistical significance(t=5.286, 4.179, 3.928, 6.734, 4.206, P<0.05). During the hospital stay, malignant arrhythmia and cardiac failure of red blood cell distribution width abnormal group were worsened or recurrent, and the death rates were 34.88%(15/43), 46.51%(20/43) and 11.63%(5/43) during the hospital stay, which were significantly higher than that of the normal group(χ2=23.653, 32.343, 4.096, P<0.05). Conclusion Compared with mild and chronic heart failure patients, the indices such as Hb, RBC, Hct, LVEF and RDW of the severe group are worse. During the hospital stay, malignant arrhythmia and heart failure of RDW abnormal group are worsened or recurrent, and the death rates are significantly higher than normal group. RDW must be correlated with the prognosis of chronic heart failure patients. Key words: Cell distribution width; Chronic heart failure; Prognosis