Abstract
Objective To observe 131I uptake rate of Graves's patients after taking lithium carbonate thyroid and to investigate application value of lithium carbonate for the low 131I uptake rate in Graves's patients. Methods Forty-six low 131I uptake Graves's patients take lithium carbonate orally after meal, three times daily, 250 mg each time, and served 10 days, detected 131I uptake rate respectively before and after lithium carbonate treatment and compared the changes. Result Low 131I uptake rate after intake of lithium carbonate with 10 days was significantly higher (27%) in 24 hours than before with a statistic difference (t=3.24, P＜0.01). Conclusions Lithium carbonate can improved the intake of thyroid 131I Graves's patients, met the requirements of patients and reduced the amount of 131I treatment. So it was valuable for clinical application. Key words: Graves disease; Lithium carbonate; Thyroid; Iodine radioisotopes
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