Application research of MR-DWI and ADC values in diagnosis of ovarian tumors

Abstract

Objective The ovarian cancer is a common malignant tumor of gynaecology, and it is lack of early specific differential diagnosis. This study is to investigate the application of MR-DWI and ADC values in diagnosis of ovarian tumors, and to provide reference for clinical diagnosis. Methods 124 patients with ovarian tumors were selected as observation group, and 45 normal women were selected as the control group during the same period. MRI was performed before operation, the lesions from and image signal of MR-DWI was analyzed, and the value of ADC was measured. Results The ovarian tissues in the observation group had high or equal signal, with round or circular ovarian tumor, and uneven cystic wall spaces, while ovarian tissues in the control group had no clear boundary, with multiple follicles and low signal. The value of ADC in the observation group was (1.49±0.23) ×10-3mm2/s, higher than that of the control group ( (0.97±0.18) ×10-3mm2/s) . The difference had statistical significance (P<0.05) . The values of ADC were lower in benign tumors than in the malignant ovarian tumors, and the difference had statistical significance (P<0.05) . For patients in the observation group, the values of ADC were higher for patients in level Ⅲ than for patients in level Ⅱ, and it was higher for patients in levelⅡ than for patients in level I, and the difference had statistical significance (P<0.05) . The values of ADC was positively correlated to ovarian tumor type (r=0.763, P<0.05) , and negatively correlated to pathological classification of ovarian tumor (r=-0.947, P<0.05) . Conclusion MR-DWI and ADC values can be used to diagnose ovarian tumors. The values of ADC are positively correlated to ovarian tumors’ classification, ie, the higher the ADC values, the higher classification the ovarian tumors. Key words: Ovarian tumors; Magnetic resonance imaging; Diffusion weighted imaging; Apparent diffusion coefficient