Abstract

There are a variety of serological changes in the blood circulation of patients with lupus nephritis, including complement, autoantibodies, immunoglobulin and cytokines and so on.These substances not only involved in the development of the disease leads to renal pathological damage, but also can be used as a biomarker to reflect changes in disease.In this paper, the detection of serum markers in lupus nephritis diagnosis, determine the pathological classification, disease activity, evaluation of therapeutic effect and prognosis were reviewed, in order to provide scientific basis for the early diagnosis and treatment of lupus nephritis by monitoring the changes of serum indicators. Key words: Lupus nephritis; Systemic lupus erythematosus; Complement; Autoantibody; Immunoglobulin; Cytokine

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