Application of UCNPs in Bio-imaging and Treatment

Abstract

Upconversion nanoparticles (UCNPs) are ideal fluorescent probes for biomedical applications owing to their good characteristics, including superior photostability, deep light penetration, low background auto-fluorescence and good biocompatibility. This chapter focuses on the recent developments of UCNPs in bioimaging and tumor therapy applications, as well as gives an analysis of the advantages of UCNPs over the conventional fluorescent materials and the biocompatibility and toxicity of UCNPs. Finally, the chapter discuss the challenges in the development of UCNPs in biomedical application.