Abstract
Objective To evaluate the outcomes of pregnancy of unknown location (PUL) with serial of serum β-human chorionic gonadotropin (β-hCG) and transvaginal sonography. Methods A retrospective study was performed to analyze the relationship between serial serum β-hCG and transvaginal sonography among 315 women who were diagnosed with nonvisible intrauterine pregnancy during Jan 2015 to Dec 2015. Results The pregnancy outcomes of 315 women included 254 intrauterine pregnancies, 43 ectopic pregnancies, and 18 spontaneously resolving miscarriages or spontaneously resolving ectopic pregnancies. The serial serum β-hCG curve was classified as rising hCG levels, declining or plateauing hCG levels. Different pregnancy outcomes could exhibit as rising or declining hCG curves. Conclusions It is critical to perform two or more serial serum β-hCG examinations followed by transvaginal sonography to establish the correct diagnosis for PUL. Key words: Ultrasonography; Chorionic gonadotropin/ME; Pregnancy, ectopic/DI/ME/US; Pregnancy outcome
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