Abstract
Thrombopoietin receptor agonist (TPORA) is a kind of medicine which can specifically combine with thrombopoietin (TPO) receptor (c-mpl) and take effect. Because of the advantages such as abundant source, easy access, no risk of donor, low requirement of human leukocyte antigen (HLA) matching, low incidence and mild degree of graft versus host disease (GVHD), etc., cord blood transplantation (CBT) has been widely applied in treatment of malignancy hematologic disease. In this paper, the biological characteristics of TPORA and its application in CBT are reviewed. Key words: Receptors, thrombopoietin; Cord blood stem cell transplantation; Graft vs host disease
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