Application of three-dimensional visualization technique in pediatric living donor liver transplantation

Abstract

To investigate the value of three-dimensional(3D) visualization technology for donor evaluation in pediatric living donor liver transplantation(LDLT). The clinical data of 348 familial donors who underwent LDLT from January 2013 to December 2015 in Renji Hospital, Shanghai Jiaotong University School of Medicine were reviewed retrospectively.3D visualize-vascular type and liver grafts volume were analyzed and compared to the actual volume and anatomy. Paired t-test was used to compared the liver volume between 3D visualization estimated-liver grafts and actual volume. Among the LDLT recipients, 168 were male and 180 were female aged from 5 to 176 months(median age 8 months), and average body weight was(9.4±5.4)kg, average abdominal circumference was (56.3±13.3)cm.Among the LDLT candidates, 131 were male and 217 were female aged from 19 to 59 years(average age (32.0±13.0)years, median age 30 years). The type of liver grafts from 348 donors included: 308 left lateral lobe(88.5%)(5 were reduced-size grafts(1.4%) and 2 were hyper reduced-size grafts (0.6%)), 32 left lobe donor(9.2%), 7 right lobe donor(2.0%) and 1 right posterior lobe donor(0.3%). The difference between the mean volume of 3D visualization estimated-liver grafts and the mean actual volume was not significant((300.3±80.7)ml vs.(287.6±71.5)ml)(P=0.15), the average weight was (291.9±75.6)g and mean graft recipient body weight ratio was (3.2±0.1)%.The mean operation time was (205±59)minutes, the mean blood loss was (153±49)ml, and the mean postoperative hospital stay was (7±3)days. 3D visualization reconstruction technique can accurately assess the donor condition and ensure the safety both donors and recipients.