Abstract
Technological advancements provide sophisticated radiotherapy modalities that promise exquisite target conformality with sparing of surrounding healthy tissue. Of interest is the radiotherapy of mobile tumors where 4D target tracking radiotherapy (4DTRT) is being developed to manage respiratory-induced organ motion. The clinical implementation of 4DTRT can be very challenging compared to conventional radiotherapy using individualized motion margins (CONV). The need to justify the added technological effort for the clinical return is an important one facing the radiotherapy community.
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