Abstract
An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL−1. Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis.
Highlights
Capillary electrophoresis is a versatile separation technique, which can be used for a wide range of substances
Some studies involve the monitoring of environmental pollutants [39]
It has been used for metal determination [40], as well as for food analysis [41, 42] and drug analysis [43,44,45,46,47]
Summary
Capillary electrophoresis is a versatile separation technique, which can be used for a wide range of substances. The technique of capillary electrophoresis has been used for the separation of drugs. In February of 2017, in Geneva, the World Health Organization (WHO) published its first ever list of antibioticresistant “priority pathogens,” a catalogue of 12 families of bacteria that pose the greatest threat to human health. Antibiotic resistance has been increasing and treatment options have been rapidly lost. The list highlights the threat of Gramnegative bacteria that are resistant to multiple antibiotics. Ertapenem sodium (ERTM) is a β-lactam antimicrobial from the carbapenem class. This class of drugs has activity against Gram-positive, Gram-negative, aerobic, and anaerobic bacteria
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
