Abstract
This paper describes the application of the Powell algorithm to the optimization of a flow injection system configuration. The performance of this algorithm has been compared with the modified simplex method. The system studied is the determination of ammonia, based on the indophenol blue reaction. A linear combination of sensitivity and sample throughput is used as the objective function because of its simultaneous optimization capability. Results obtained show that the proposed method may reach the optimal conditions with a lower number of experimental evaluations.
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