Abstract
As a novel, label-free and non-invasive detection modality, terahertz (THz, 1THz=1012Hz) spectroscopy has been widely used in various areas. For instance, in the biomedical field, it has great potentials to provide real-time scanning of living cells and tissues due to its unique advantages. Significant achievements have been reached in cell detection, related to bacterial identification, cancer cell characterization and blood cell detection. In tissue detection, the THz spectroscopy can be used to provide real-time scanning of living tissues and fast diagnosis. Furthermore, a single system which integrated THz spectroscopy and THz imaging would be able to collect information more sensitive and comprehensive. However, the clinical adaption of THz spectroscopy is still a controversial issue attributed to some intrinsic limitations and technical bottlenecks. In this article, both the application of THz spectroscopy in cell and tissue detection and the existing challenges and strategies to accelerate clinical applications were reviewed comprehensively.(Chin J Lab Med, 2018, 41: 348-351) Key words: Spectrum analysis; Biosensing techniques
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