Abstract
Objective: To explore the application value of electrocardiograph (ECG) T-wave Alternans (TWA) anomaly in acute stage of intracerebral hemorrhage patients. Methods: We choose 1175 intracerebral hemorrhage patients whose conventional 12-lead ECG has TWA in our hospital from January 2011 to December 2015, 751 patients without TWA in the same period as the control group, compared the volume of intracerebral hemorrhage, bleeding site and mortality between the 2 groups. Results: In TWA group, 247 cases died, 361 cases with massive intracerebral hemorrhage, 298 cases with brain stem hemorrhage; in TWA negative group (control group), 41 cases died, 93 cases with massive brain hemorrhage, 64 cases with brain stem hemorrhage. There are statistical differences between two groups (P < 0.05). Multi factor Logistic regression analysis showed that massive intracerebral hemorrhage, brain stem hemorrhage, Glasgow score and TWA were the independent factors in the prognosis of intracerebral hemorrhage (P < 0.05). Conclusion: The occurrence of TWA is significantly related to the volume of bleeding, the bleeding site and mortality, and can be used as an important parameter in the prognosis of intracerebral hemorrhage.
Highlights
Intracerebral hemorrhage is a disease with high mortality
Multi factor Logistic regression analysis showed that massive intracerebral hemorrhage, brain stem hemorrhage, Glasgow score and T-wave Alternans (TWA) were the independent factors in the prognosis of intracerebral hemorrhage (P < 0.05)
3) Multivariate logistic regression analysis showed that massive intracerebral hemorrhage, brain stem hemorrhage, Glasgow score and TWA were the independent factors in the prognosis of intracerebral hemorrhage (P < 0.05)
Summary
The ECG often changes, which is related to the high mortality of intracerebral hemorrhage. We discussed the relationship between TWA and cerebral hemorrhage site and hemorrhage volume of 65 cases [1], the sample size is small, and it’s not clear whether it can be used as an indicator of prognosis of patients with cerebral hemorrhage. As we retrospectively analyze our hospital intracerebral hemorrhage patients in conventional 12 lead ECG TWA incidence and its relationship with prognosis from January 2011 to December 2015. We judge its value to evaluate the prognosis of intracerebral hemorrhage.
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