Application of Supramolecular Polymer Nanoparticles in Controlled Release System of Anticancer Drugs

Abstract

Nanoscience is a comprehensive, interdisciplinary course based on many advanced sciences and technologies that has developed rapidly in recent decades. Nanotechnology has been widely used in biomedicine, materials science, chemistry, physics, information and electronic engineering, and other fields. Nanomaterials have been widely used in various research fields because of their many excellent properties, such as quantum size phenomenon, small size phenomenon, and quantum mechanics. Surface effects and tunneling phenomena have now become the focus of scientific research. Controlled release means that the drug is released quantitatively and uniformly through the controlled release coating film, so that the concentration of the drug in the blood remains unchanged. This paper is aimed at studying the application and performance of nanoparticles in the controlled release system of anticancer drugs. This paper addresses the issue of the controlled release of anticancer drugs. This question is based on nanoparticles. Therefore, it was elaborated around supramolecular polymer nanoparticles, and a case design and analysis of its use in the controlled release system of anticancer drugs was carried out. The experimental results showed that when laser irradiation and GSH coexisted, the dissolution rate and cumulative dissolution rate of DOX were the highest, and the total release within 3 h was close to 53%. This result indicates that the release of DOX from DOX@HMPB@PEI-SS-HA is both photosensitivity and redox responsive, and the photosensitivity predominates.