Abstract
Objective To estimate the value of superb microvascular imaging(SMI) in the detection of microvascular flow signal of focal liver lesions(FLLs). Methods A total of 54 patients with 56 FLLs who had underwent CDFI(Color Doppler Flow imaging) and SMI were included in this study. Adler semi-quantitative assessment was used to grade the distribution of blood flow signal for each FLL by two observers, then inter-observer agreement was assessed. The distribution of blood flow grade between CDFI and SMI was also compared with contrast-enhanced ultrasound(CEUS) as the reference standard. Results The inter-observer agreement for Adler semi-quantitative grading were fair (Κ=0.579) on CDFI and good (Κ=0.605) on SMI, respectively. The grade 0, Ⅰ, Ⅱ and Ⅲ of Adler semi-quantitative grading of all total 56 FLLs' blood flow signal on three flow imaging tools were 4(7.14%), 25(42.86%), 14(25%), 14(25%)on CDFI, 0(0%), 12(21.43%), 12(19.64%), 33(58.93%) on SMI, and 0(0%), 3(5.36%), 21(37.50%), 32(57.14%) on CEUS micro-flow imaging, respectively. With CEUS blood flow distribution in the arterial phase as the reference, the coincidence rate of CDFI was 30.35%, while that of SMI was 73.21%. The distinction of ability on FLL's micro-vascular imaging between CDFI and SMI was statistically significant(P<0.01). Conclusions The inter-observer agreement of SMI was better than that of CDFI and its capacity in displaying FLL's micro-vascular was superior to CDFI, SMI can exhibit more tiny vessels and thus SMI may possess potential value in the differential diagnosis of FLLs. Key words: Ultrasonography; Focal liver lesions; Superb microvascular imaging
Published Version
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